Chandigarh: Adenomyosis is a common condition in which the inner lining of the uterus (the endometrium) breaks through the muscle wall of the uterus (the myometrium). Adenomyosis can cause menstrual cramps, lower abdominal pressure, and bloating before menstrual periods and can result in heavy periods. The condition can be located throughout the entire uterus or localized in one spot. In India alone, there are more than one million cases reported.
The disease has always been considered the classic condition of multiparous women over 40 years old who have pain and heavy menstrual bleeding, diagnosed at hysterectomy, the epidemiological scenario has completely changed. Of late, adenomyosis is increasingly been identified in young women with pain, abnormal uterine bleeding, infertility, or no symptoms by using imaging techniques such as transvaginal ultrasound and magnetic resonance.
Dr. Ankush Raut, Senior Consultant IVF at Medicover Fertility Chandigarh said, “patients with adenomyosis who previously had multiple unsuccessful IVF cycles can have a successful pregnancy with ART after prolonged down-regulation with GnRH-a and PRP (platelet rich plasma) therapy.
“With the European standard of operating protocols which have been designed and validated over 24 years in multiple European countries under the guidelines of the European Society of Human Reproduction and Embryology (ESHRE), the medical team at Medicover Fertility India has been able to achieve a higher success rate,” he added.
The condition is commonly described as the presence of endometrial glands and stroma located deep within the myometrium, associated with smooth muscle hyperplasia. This is due to the invasion of myometrium by basal glands and stroma with destruction of normal myometrium architecture. According to data from FOGSI, Adenomyosis is considered relatively common but its exact incidence has not been accurately determined and ranges from 5 % to 70 % in symptomatic women.
According to Dr. Promila Jindal, Medical Director – Punjab, “There are significantly lower clinical pregnancy rates in women with adenomyosis diagnosed by ultrasound (23.6%) compared with the nonadenomyosis group (44.6%). ”
“In a recent cross-sectional study on infertile women, it was observed that adenomyosis prevalence were 24.4% in women at least 40 years old and 22% in women less than 40 years old. This percentage increased to 38.2% in cases of recurrent pregnancy loss and to 34.7% in previous ART failure.”
Thus, infertile women who experience adenomyosis can achieve pregnancy after being treated with different strategies. Furthermore, surgery could be effective in women with adenomyosis with a history of IVF failure, although latter finding could be partly attributed to the higher rate of early diagnosis.
Medicover is a leading international Healthcare and Diagnostic Services company founded in 1995. Medicover operates a large number of ambulatory clinics, hospitals, specialty-care facilities and laboratories, and its largest markets are Poland and Germany. In 2018, Medicover had a revenue of EUR 672 million and 20,970 employees. In India, Medicover Fertility operates 16 clinics, including one each at Chandigarh, Ludhiana and Jalandhar.